Nicole Richie
As Heather Chandler
A former high school classmate (and bully) of Sarah's, Heather came back into her life as an agent of Fulcrum.

Jordana Brewster
As Dr. Jill Roberts
She used to be the love of Chuck’s life, before Sarah. And then she was revealed to be a Fulcrum agent. Love hurts.

Angie Harmon
As Sydney Prince
She ran the Ring’s Los Angeles cell and attempted to recruit Awesome as a spy.

Bianca Chiminello
As Juliette
Tried to heist a microchip that held an Intersect upgrade.

Bo Derek
As Bo Derek
Times were hard for this former supermodel, so she began a side career in espionage. Bad Bo.

India de Beaufort
As Jasmine
She’s really good with knives. And really pretty. In Chuck-world, that’s enough.

Jenny McCarthy
As Sylvia Arculin
Working for FULCRUM, she was part of a team that tried to develop a rival Intersect program to create their own super agent.

Josie Davis
As Serena
A Ring agent who posed as a stewardess to help escort the key to the Ring Intelligence Safe to Paris.

Karolína Kurková
As Sofia Stepanova
Being a high-fashion runway model is a cover for her to transport arms around the world.

Katrina Law
Alexis White
A Fulcrum torturer who kills herself to avoid being captured by Chuck and the team.

Lauren Cohan
As Vivian McArthur Volkoff
The daughter of criminal mastermind Alexei Volkoff who eventually would embrace her nefarious birthright.

Lorena Bernal
As Malena Bernal
Another one in a long line of sexy arms dealers, she also went by the name La Ciudad.

Melinda Clarke
As Sasha Banicheck
A KGB agent-turned-mercenary whose preferred method of attack was seduction.

Monet Mazur
As Barbara
Volkoff’s right-hand woman who infiltrates the Buy More by offering to do “anything” for a new smart phone.

Mircea Monroe
As Amy
Part of Sarah’s old group of female spies, the C.A.T. Squad, who turned went bad.

Noureen DeWulf
As Lizzie
Her cover was as a Pita Palace delivery girl, but her target was the Intersect.

Rebecca Romijn
As Robyn Cunnings
A rogue CIA agent who, while trying to nab Chuck and Sarah, kidnapped Ellie and Awesome instead.

Robin Givens
As Jane Bentley
The head of a government program that fielded a host of Intersect-ed agents without Chuck’s aversion to collateral damage.